Manganese(ii)-catalyzed modular synthesis of isoquinolines from vinyl isocyanides and hydrazines. Issue 4 (2nd March 2016)

• Record Type: Journal Article
• Authors: Mao, Hong; Gao, Mingchun; Liu, Bingxin; Xu, Bin
• Is Part Of: Organic chemistry frontiers. Volume 3:Issue 4(2016:Apr.)
• Page Start: 516
• Page End: 521
• Publication Date: 2016-03-02
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c6qo00048g
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : An efficient manganese(ii )-catalyzed oxidative radical cascade reaction was developed from vinyl isocyanides and hydrazines leading to the modular synthesis of multi-substituted isoquinolines, phenanthridines and pyrrolo[1, 2- a ]quinoxalines. Abstract : An efficient manganese(ii )-catalyzed oxidative radical cascade reaction was developed for the modular synthesis of multi-substituted isoquinolines from easily accessible vinyl isocyanides and hydrazines. Pyrrolo[1, 2- a ]quinoxalines and phenanthridines could also be afforded efficiently by this method and a wide range of alkyl, (hetero)aryl and alkoxycarbonyl substitutions could be easily introduced.