Liposome-induced exfoliation of graphite to few-layer graphene dispersion with antibacterial activity. Issue 31 (21st July 2015)

• Record Type: Journal Article
• Authors: Zappacosta, R.; Di Giulio, M.; Ettorre, V.; Bosco, D.; Hadad, C.; Siani, G.; Di Bartolomeo, S.; Cataldi, A.; Cellini, L.; Fontana, A.
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 31(2015)
• Page Start: 6520
• Page End: 6527
• Publication Date: 2015-07-21
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c5tb00798d
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Liposome-induced exfoliation of graphite allowed to obtain few-layer graphene homogeneous in size and hydrophilic due to the non-covalent functionalization with phospholipids. The corresponding dispersions are stable for 48 h and demonstrate antimicrobial activity. Abstract : Few-layer graphene aqueous dispersions are obtained by exploiting liposomes as effective exfoliating agents for graphite. Raman measurements evidence the presence of non-oxidized double layer graphene as well as amphiphilic phospholipid molecules organized in bilayers in the samples. TEM analyses confirmed that the obtained homogeneous graphene nanosheets are embedded in the liposomal bilayer. The as-prepared graphene aqueous dispersion is stable for days and demonstrates significant antibacterial activity against both Gram-positive ( Staphylococcus aureus ) and Gram-negative ( Escherichia coli ) strains, with a reduction in the growth of S. aureus and E. coli as high as 60 and 78%, respectively.