Ligation driven 19F relaxation enhancement in self-assembled Ln(iii) complexes. Issue 14 (14th January 2015)

• Record Type: Journal Article
• Authors: Davies, Gemma-Louise; Brown, Asha; Blackburn, Octavia; Tropiano, Manuel; Faulkner, Stephen; Beer, Paul D.; Davis, Jason J.
• Is Part Of: Chemical communications. Volume 51:Issue 14(2015)
• Page Start: 2918
• Page End: 2920
• Publication Date: 2015-01-14
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc09952d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Strong bidentate ligation of a fluorinated isophthalate with a binuclear lanthanide chelate results in the paramagnetic relaxation enhancement of 19 F, providing a promising route to a generation of self-assembled 19 F contrast agents. Abstract : Strong bidentate ligation between a fluorinated isophthalate and binuclear lanthanide-DO3A species yields a new class of 19 F NMR agent with very high nuclear relaxation rates at physiologically-relevant pH.