A novel chiral electrochemiluminescence sensor that can discriminate proline enantiomers. Issue 114 (3rd November 2015)

• Record Type: Journal Article
• Authors: Wang, Qinghong; Lin, Xia; Guo, Dongmei; Xu, Juanjuan; Xuan, Chunzhi; Chen, Cui; Fu, Yingzi
• Is Part Of: RSC advances. Volume 5:Issue 114(2015)
• Page Start: 94338
• Page End: 94343
• Publication Date: 2015-11-03
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra13528a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A chiral stereoselective electrochemiluminescence (ECL) sensor was constructed by using Ru–AuNPs and β-CD–rGO composites to discriminate proline enantiomers. Abstract : A sensitive, stable and stereoselective electrochemiluminescence (ECL) sensor has been designed to enantioselectively discriminate proline enantiomers by immobilizing Ru(bpy)3 2+ –gold nanoparticles (Ru–AuNPs) and β-cyclodextrin–reduced graphene oxide (β-CD–rGO) on glassy carbon electrode. More Ru(bpy)3 2+ could be immobilized on the surface of electrode stably via preparing Ru–AuNPs and better stereoselectivity could be introduced to the sensor via the synthesis of β-CD–rGO. When the developed sensor interacted with proline enantiomers, obvious difference of ECL intensities towardsl - andd -proline was observed, and a larger intensity was obtained fromd -proline. As a result, ECL technique might act as a promising method to chiral recognition of amino acids enantiomers or chiral drugs.