Quantitative assessment of synovitis in Legg–Calvé–Perthes disease using gadolinium-enhanced MRI. Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Neal, David C.; O'Brien, Jack C.; Burgess, Jamie; Jo, Chanhee; Kim, Harry K.W.
• Is Part Of: Journal of pediatric orthopedics. Volume 24:Issue 2(2015)
• Publication Date: 2015-03
• Subjects: avascular necrosis -- gadolinium-enhanced MRI -- hip synovitis -- Legg–Calvé–Perthes disease -- osteonecrosis; Pediatric orthopedics -- Periodicals; 618.927005
• DOI: 10.1097/BPB.0000000000000107
• Languages: English
• ISSNs: 1060-152X

Abstract

Abstract : A quantitative method to assess hip synovitis in Legg–Calvé–Perthes disease (LCPD) is not currently available. To develop this method, the areas of synovial enhancement on gadolinium-enhanced MRI (Gd-MRI) were measured by two independent observers. The volume of synovial enhancement was significantly increased in the initial and the fragmentation stages of LCPD (Waldenström stages I and II), with a persistence of synovitis into the reossification stage (stage III). The Gd-MRI method had high interobserver and intraobserver agreements and may serve as a useful method to monitor the effect of various treatments on hip synovitis in LCPD.