A Rare Pediatric Example of Subcutaneous Extraskeletal Osteosarcoma: A Case Report and Review of the Morphologic Differential Diagnosis. (April 2016)

• Record Type: Journal Article
• Authors: Zreik, Riyam T.; Meyer, Reid G.; Jenkins, Robert B.; Norambuena, Germán A.; Fritchie, Karen J.
• Is Part Of: American journal of dermatopathology. Volume 38:Number 4(2016)
• Publication Date: 2016-04
• Subjects: extraskeletal osteosarcoma -- subcutaneous -- pediatric -- childhood; Skin -- Diseases -- Periodicals; Histology, Pathological -- Periodicals; 616.50705
• DOI: 10.1097/DAD.0000000000000458
• Languages: English
• ISSNs: 0193-1091

Abstract

Abstract : Abstract: Primary extraskeletal osteosarcoma is an exceedingly rare malignant neoplasm that accounts for approximately 1% of soft tissue sarcomas and most often occurs in the deep soft tissues of adults. Extraskeletal osteosarcoma is characterized by the production of osteoid, bone, and/or chondroid matrix. The diagnosis of extraskeletal osteosarcoma requires careful radiologic and clinical correlation to ensure that the patient does not have an underlying bone primary. This is a case report of primary subcutaneous extraskeletal osteosarcoma arising in the thigh of a 15-year-old girl with a complex karyotype, and the morphologic differential diagnosis is reviewed.