Decellular Nerve Allografts. Issue 11 (November 2015)

• Record Type: Journal Article
• Authors: Tang, Peter; Chauhan, Aakash
• Is Part Of: Journal of the American Academy of Orthopaedic Surgeons. Volume 23:Issue 11(2015)
• Publication Date: 2015-11
• Subjects: Peripheral nerve injury -- acellular nerve allograft -- decellular nerve allograft -- repair -- regeneration; Orthopedics -- Periodicals; Orthopedic surgery -- Periodicals; Joint Diseases -- Periodicals; Orthopedics -- Periodicals; Orthopedic surgery; Orthopedics; Periodicals; 616.7005
• DOI: 10.5435/JAAOS-D-14-00373
• Languages: English
• ISSNs: 1067-151X

Abstract

Abstract : Multiple treatment options are available for patients who have peripheral nerve injuries with a gap. Decellular nerve allografts are one option and provide an extracellular scaffold for neuronal cells to migrate for axonal regrowth. Immunosuppression is not needed because improved nerve processing technologies have rendered decellular nerve allografts nonimmunogenic. These allografts have also shown promising results in both animal and human studies as an alternative repair option.