Associations Between Metabolic and Aerobic Fitness Parameters in Patients With Schizophrenia. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Vancampfort, Davy; Guelinkcx, Hannes; Probst, Michel; Stubbs, Brendon; Rosenbaum, Simon; Ward, Philip B.; De Hert, Marc
• Is Part Of: Journal of nervous and mental disease. Volume 203:Issue 1(2015:Jan.)
• Publication Date: 2015-01
• Subjects: Exercise -- physical activity -- metabolic syndrome -- physical fitness -- psychosis -- schizophrenia; Neurology -- Periodicals; Psychiatry -- Periodicals; Neurology; Psychiatry; Neurologie; Psychiatrie; Neurology; Psychiatry; Periodicals; 616.8005
• DOI: 10.1097/NMD.0000000000000229
• Languages: English
• ISSNs: 0022-3018

Abstract

Abstract : Abstract: The primary aim was to determine whether the presence of metabolic syndrome (MetS) limits aerobic fitness in patients with schizophrenia. A secondary aim was to investigate the associations between aerobic fitness and MetS parameters. Aerobic fitness (expressed as predicted maximal oxygen uptake) was assessed using the Astrand-Rhyming test. Those with MetS ( n = 19) were similar in age, sex, antipsychotic medication use, symptoms, and smoking behavior than those without ( n = 31). Estimated maximal oxygen uptake was 21.4% lower ( p = 0.001) in patients with MetS than in patients without MetS (29.5 ± 7.4 ml of O2 /min/kg vs . 37.5 ± 8.2 ml of O2 /min/kg, respectively). The estimated maximal oxygen uptake of the entire sample was correlated with waist circumference, the level of high-density lipoproteins, and fasting glucose. The current study demonstrates that the additive burden of MetS might place people with schizophrenia at increased risk for functional limitations in daily life activities.