Potential Applications of Using 68Ga–Evans Blue PET/CT in the Evaluation of Lymphatic Disorder: Preliminary Observations. (April 2016)

• Record Type: Journal Article
• Authors: Zhang, Wei; Wu, Peilin; Li, Fang; Tong, Guansheng; Chen, Xiaoyuan; Zhu, Zhaohui
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 4(2016)
• Publication Date: 2016-04
• Subjects: 68Ga -- chyloperitoneum -- chylothorax -- Evans blue -- lymphangioleiomyomatosis -- lymphedema, chylothorax, chyloperitoneum -- lymphoscintigraphy -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001171
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Purpose: Potentials of 68 Ga-NEB as a PET tracer in the evaluation of a variety of lymphatic drainage disorders were analyzed. Methods: 68 Ga-NEB was injected subcutaneously, and the PET/CT images were acquired in 13 patients with different suspected lymphatic drainage abnormality. The 68 Ga-NEB PET/CT findings were compared with 99m Tc-SC lymphoscintigraphy. Results: 68 Ga-NEB activity could be clearly observed in the lymphatic route on the PET/CT images from all the patients. In 5 (38.5%) of 13 patients tested, 68 Ga-NEB PET/CT provided more information than the 99m Tc-SC lymphoscintigraphy. Conclusions: 68 Ga-NEB PET/CT can be used as an alternative of 99m Tc-SC lymphoscintigraphy in the evaluation of lymphatic disorders, which enables fast results and might be more accurate than the conventional 99m Tc-SC lymphoscintigraphy.