How to Manage Electrical Status Epilepticus in Sleep. Issue 1 (February 2016)

• Record Type: Journal Article
• Authors: Veggiotti, Pierangelo; Pera, Maria Carmela; Olivotto, Sara; De Giorgis, Valentina
• Is Part Of: Journal of clinical neurophysiology. Volume 33:Issue 1(2016)
• Publication Date: 2016-02
• Subjects: E-SES -- Neuropsychologic assessment -- Spike-wave index -- Clobazam -- Methylprednisolone; Electroencephalography -- Periodicals; Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electroencephalography; Periodicals; 612.805
• DOI: 10.1097/WNP.0000000000000235
• Languages: English
• ISSNs: 0736-0258

Abstract

Abstract : Summary: Electrical status epilepticus in sleep is an age-dependent syndrome with the characteristic pattern of continuous spike and waves during non–rapid eye movement sleep. Most children can present developmental deterioration. The demonstration of the EEG pattern has to rely on all night long EEG recordings. A comprehensive neuropsychologic evaluation with periodic reassessment should be performed. For the idiopathic forms of electrical status epilepticus in sleep, clobazam could be considered as the first-line therapy; in the other cases, corticosteroids, in particular intravenous methylprednisolone pulse therapy, remain the most effective and should be considered the therapy of choice.