Aggressive esthesioneuroblastoma with divergent differentiation: A taxonomic dilemma. (1st November 2016)

• Record Type: Journal Article
• Authors: Charles, Norman C.; Petris, Carisa K.; Kim, Eleanore T.
• Is Part Of: Orbit. Volume 35:Number 6(2016)
• Page Start: 357
• Page End: 359
• Publication Date: 2016-11-01
• Subjects: Esthesioneuroblastoma -- olfactory neuroblastoma; Eye-sockets -- Surgery -- Periodicals; Eye-sockets -- Diseases -- Periodicals; Orbit -- surgery -- Periodicals; Orbital Diseases -- Periodicals; 617.7
• DOI: 10.1080/01676830.2016.1193537
• Languages: English
• ISSNs: 0167-6830

Abstract

ABSTRACT: The authors describe an esthesioneuroblastoma (olfactory neuroblastoma) that occurred within the nasal cavity and brain in a 31-year-old man. Following excision, the tumor recurred in the left orbit and in mediastinal lymph nodes. Treatment included orbital excision and systemic chemotherapy. Histopathology showed a high-grade neuroepithelial tumor with positive immunohistochemical markers for neuroendocrine and epithelial components, an unusual combination raising issues concerning taxonomy.