Orbital IgG4-Related Disease Detected by 11C-Methionine PET/CT. (October 2015)

• Record Type: Journal Article
• Authors: Yamane, Tomohiko; Seto, Akira; Suzuki, Tomonari; Yokota, Kazuhiro; Li, Chih-Ping; Mimura, Toshihide; Kuji, Ichiei
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 10(2015)
• Publication Date: 2015-10
• Subjects: 11C-methionine -- PET -- 18F-FDG -- IgG4-related disease -- orbit; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000842
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 64-year-old man presented with a complaint of left exophthalmos. Whole-body 18 F-FDG PET/CT showed increased uptake in the soft tissue masses in the orbits, peripancreas, and left renal hilum. 11 C-methionine (MET) PET/CT of the head and neck showed increased uptake in the orbits, and the SUVmax of the left orbital lesion was 7.0. The patient was finally diagnosed as IgG4-related disease by the results of increased serum IgG4 and the biopsy of the orbital lesion. Although 11 C-MET is generally considered as a tumor-specific tracer, fibrous tissues of IgG4-related disease may be visualized by 11 C-MET PET/CT.