Sex steroid hormone secretion in the wall lizard Podarcis sicula testis: The involvement of VIP. Issue 10 (9th September 2015)

• Record Type: Journal Article
• Authors: Rosati, Luigi; Prisco, Marina; Di Fiore, Maria Maddalena; Santillo, Alessandra; Sciarrillo, Rosaria; Valiante, Salvatore; Laforgia, Vincenza; Coraggio, Francesca; Andreuccetti, Piero; Agnese, Marisa
• Is Part Of: Journal of experimental zoology. Volume 323:Issue 10(2015)
• Page Start: 714
• Page End: 721
• Publication Date: 2015-09-09
• Subjects: Zoology -- Periodicals; Ecological genetics -- Periodicals; Ecophysiology -- Periodicals; 571.105
• DOI: 10.1002/jez.1964
• Languages: English
• ISSNs: 1932-5223

Abstract

ABSTRACT: Vasoactive intestinal peptide (VIP) is a pleiotropic neuropeptide involved in different functions, including testosterone synthesis. Recently, we reported the presence of VIP in the testis of Podarcis sic ula, throughout the reproductive cycle. Now, we investigated the effects of the VIP on steroidogenesis in significant periods of the Podarcis reproductive cycle: winter stasis, reproductive period, and summer stasis. Using VIP treatments in testis culture in absence or presence of receptors antagonists, we demonstrated for the first time that in P . sic ula, VIP is involved not only in testosterone synthesis, as in mammals, but in 17β‐estradiol synthesis too. J. Exp. Zool. 323A: 714–721, 2015 . © 2015 Wiley Periodicals, Inc.