Peripheral Neuropathy Associated With Ipilimumab: A Report of 2 Cases. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Thaipisuttikul, Iyavut; Chapman, Paul; Avila, Edward K.
• Is Part Of: Journal of immunotherapy. Volume 38:Issue 2(2015:Feb./Mar.)
• Publication Date: 2015-02
• Subjects: ipilimumab -- melanoma -- sensorimotor polyneuropathy; Immunotherapy -- Periodicals; Immunotherapy -- Periodicals; Neoplasms -- therapy -- Periodicals; Electronic journals; Electronic journals; 615.37
• DOI: 10.1097/CJI.0000000000000070
• Languages: English
• ISSNs: 1524-9557

Abstract

Abstract : Ipilimumab, a monoclonal antibody targeting human cytotoxic T-lymphocyte–associated antigen 4, was approved by the FDA and European Medicines Agency for the treatment of metastatic melanoma. Immune-related adverse effects can occur with the use of this agent, but peripheral nervous system problems are rare. We report 2 cases of ipilimumab-induced polyneuropathy.