Spinal Intramedullary Metastatic Small Cell Lung Cancer Mimicking Ependymoma on Frozen Biopsy During Surgery: A Case Report. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Park, Jin Hoon; Eom, Dae-Woon; Jung, Sang Ku; Kang, Hui Dong; Oh, Se Hyun; Hwang, In Seok; Jeon, Sang Ryong
• Is Part Of: Neurosurgery quarterly. Volume 25:Issue 1(2015)
• Publication Date: 2015-02
• Subjects: intramedullary spinal cord metastasis -- small cell lung cancer -- ependymoma -- frozen biopsy -- histology; Nervous system -- Surgery -- Periodicals; 617.4805
• DOI: 10.1097/WNQ.0000000000000013
• Languages: English
• ISSNs: 1050-6438

Abstract

Abstract : A 70-year-old man presented with a 2-month history of progressive weakness of his arm and leg. During surgery, a frozen biopsy revealed an ill-defined rosette-like structure, mitosis, and hypervascularity. A diagnosis of ependymoma was made and a gross total resection was performed. However, the result of the definitive biopsy was not ependymoma, but small cell lung cancer. This report highlights the need for a close clinicopathologic correlation to enable the correct intraoperative frozen section diagnosis of spinal tumors, including a careful examination of the histologic features and operative and radiologic tumor findings.