Air Pollution and the Risk of Birth Defects in Anqing City, China. Issue 4 (April 2016)

• Record Type: Journal Article
• Authors: Yao, Cijiang; Chen, Yanyan; Zhu, Xiaoxia; Liu, Ying; Zhang, Jian; Hou, Lijuan; Xu, Yachun; Zhang, Chao; Cao, Jiyu
• Is Part Of: Journal of occupational and environmental medicine. Volume 58:Issue 4(2016)
• Page Start: e124
• Page End: e127
• Publication Date: 2016-04
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; Occupational Medicine -- Periodicals; Environmental Medicine -- Periodicals; Environmental health; Medicine, Industrial; Periodicals; Electronic journals; 616.9803
• DOI: 10.1097/JOM.0000000000000676
• Languages: English
• ISSNs: 1076-2752

Abstract

Abstract : Objective: This study aimed to explore evidence for the influence of air pollution on the risk of birth defects in China and contribute to establish prevention strategies. Methods: We conducted a retrospective cohort study in Anqing city, Eastern China, from 2010 to 2012. Binary logistic regression models were used to estimate odds ratios (ORs) per 10 μg/m3 change for SO2, NO2, and PM10 . Results: For continuous exposure to SO2 (10 μg/m 3 increase), the adjusted OR for birth defects is 1.20 [95% confidence interval (95% CI) 1.09 to 1.29] in the preconception. A 10 μg/m 3 increase in SO2 (adjusted OR 1.26, 95% CI 1.15 to 1.36) during the second trimester is strongly associated with birth defects. No associations have been observed for NO2 and PM10 . Conclusion: The results suggested that exposure to ambient SO2 during pregnancy may increase the risk of birth defects.