Cancer Treatment: Dual‐Stage‐Light‐Guided Tumor Inhibition by Mitochondria‐Targeted Photodynamic Therapy (Adv. Funct. Mater. 20/2015). (May 2015)

• Record Type: Journal Article
• Authors: Han, Kai; Lei, Qi; Wang, Shi‐Bo; Hu, Jing‐Jing; Qiu, Wen‐Xiu; Zhu, Jing‐Yi; Yin, Wei‐Na; Luo, Xu; Zhang, Xian‐Zheng
• Is Part Of: Advanced functional materials. Volume 25:Number 20(2015)
• Page Start: 2942
• Page End: 2942
• Publication Date: 2015-05
• Subjects: mitochondria‐target -- photochemical internalization -- photodynamic therapy -- proapoptosis peptide -- synergistic therapy; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201570133
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In situ mitochondria photodynamic therapy is demonstrated to be a simple but effective strategy to inhibit tumor growth. On page 2961, X.‐Z. Zhang and co‐workers construct a mitochondria‐targeted self‐delivery system for tumor therapy and imaging. In addition, a dual‐stage light irradiation strategy is developed to optimize the antitumor effect both in vitro and in vivo.