Autoimmune Retinopathy in a Patient with Autoimmune Polyendocrine Syndrome Type I. (1st April 2013)

• Record Type: Journal Article
• Authors: Breunig, Adam; Lee, Michael S.; Miller, Bradley S.; Binstadt, Bryce A.; Anderson, Mark S.; Montezuma, Sandra
• Is Part Of: Ocular immunology and inflammation. Volume 21:Number 2(2013)
• Page Start: 153
• Page End: 157
• Publication Date: 2013-04-01
• Subjects: AIR: Autoimmune retinopathy -- AIRE: Autoimmune regulator gene; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2012.754906
• Languages: English
• ISSNs: 0927-3948

Abstract

Abstract: Purpose : To present a case of autoimmune retinopathy resulting from a mutation in the autoimmune regulator (AIRE) gene. Design : Case Study Methods : Case Review Results : Mild improvement of goldmann visual field following treatment with systemic and local immunosuppression. Conclusions : There are a limited number of cases linking autoimmune retinopathy with a mutation in the AIRE gene. Further research is needed to find more effective treatment and to prevent tissue damage.