Clinical Risk Factors for Preeclampsia Determined in Early Pregnancy: Systematic Review and Meta-Analysis of Large Cohort Studies. Issue 1 (March 2017)

• Record Type: Journal Article
• Authors: Bartsch, Emily; Medcalf, Karyn E.; Park, Alison L.; Ray, Joel G.
• Is Part Of: Obstetric anesthesia digest. Volume 37:Issue 1(2017:Mar.)
• Publication Date: 2017-03
• Subjects: Preeclampsia/Eclampsia; Anesthesia in obstetrics -- Periodicals; Anesthesia in obstetrics -- Abstracts -- Periodicals; 617.968205
• DOI: 10.1097/01.aoa.0000511997.60775.68
• Languages: English
• ISSNs: 0275-665X

Abstract

Abstract : ( BMJ. 2016;353:i1753) Earlier studies have reported the effectiveness of aspirin in preventing preeclampsia in women considered to be at moderate to high risk of developing this disorder. This current study was a meta-analysis of cohort studies examining risk factors for preeclampsia with the goal of estimating early in pregnancy (⩽16 wk gestation) a woman's risk of developing preeclampsia based on the presence of absence of various risk factors. Three practical estimates were generated: the absolute risk of developing preeclampsia in the presence or absence of a given risk factor; the relative risk in the presence or absence of a given risk factor, and the population attributable fraction (PAF) for preeclampsia in relation to each risk factor. On the basis of their analysis, the authors aimed to provide a list of risk factors that could be used to identify those women at high risk for developing preeclampsia.