Prolonged Latency of Preterm Prelabour Rupture of Membranes and Neurodevelopmental Outcomes: A Secondary Analysis. Issue 2 (June 2017)

• Record Type: Journal Article
• Authors: Drassinower, D.; Friedman, A.M.; Običan, S.G.; Levin, H.; Gyamfi-Bannerman, C.
• Is Part Of: Obstetric anesthesia digest. Volume 37:Issue 2(2017:Jun.)
• Publication Date: 2017-06
• Subjects: Neonatal Morbidity and Mortality -- Obstetric Complications; Anesthesia in obstetrics -- Periodicals; Anesthesia in obstetrics -- Abstracts -- Periodicals; 617.968205
• DOI: 10.1097/01.aoa.0000515757.75824.79
• Languages: English
• ISSNs: 0275-665X

Abstract

Abstract : ( BJOG . 2016;123(10):1629–1635) Neurodevelopmental delay is multifactorial and can result from a variety of disturbances to the developing fetal brain. Preterm prelabor rupture of membranes (PPROM) that leads to spontaneous preterm birth is often associated with inflammation and infection. As PPROM and neurodevelopmental delay are both associated with inflammation and infection, it has been suggested that prolonged PPROM could be an independent risk factor for neurodevelopmental delay, separate from the increased risk associated with preterm birth. This study aimed to investigate whether prolonged exposure of the fetus in utero to PPROMs was associated with an increased risk of neurodevelopmental delay.