630: MAJOR BLEED RISK IN PATIENTS ON NOVEL ORAL ANTICOAGULANTS WITH PGP AND/OR CYP450 3A4 INHIBITORS. Issue 12 (December 2015) - Liang, Debbie; Peak, Jared; Lumbert, Kevin; Girardeau, Caroline; Gharkholonarehe, Nastaran; Gross, Jeffrey; Smith, S. Wayne