Virus-related Merkel cell carcinoma complicating fingolimod treatment for multiple sclerosis. (13th December 2016)

• Record Type: Journal Article
• Authors: Beadnall, Heidi N.; Gill, Anthony J.; Riminton, Sean; Barnett, Michael H.
• Is Part Of: Neurology. Volume 87:Number 24(2016)
• Page Start: 2595
• Page End: 2597
• Publication Date: 2016-12-13
• Subjects: Neurology -- Periodicals; Neurology -- Periodicals; Neurologie -- Périodiques; 616.8
• DOI: 10.1212/WNL.0000000000003434
• Languages: English
• ISSNs: 0028-3878

Abstract

Abstract : Idiopathic REM sleep behavior disorder (iRBD) is a rare disease (0.0038%–0.005%). 1 In patients with narcolepsy type 1 (NT1), symptomatic RBD is a frequent, comorbid disease, ranging from 45% to 61%. 2 iRBD is a premotor stage of neurodegenerative disease. Few patients with narcolepsy develop Alzheimer disease or Parkinson disease. 3 Treatment studies in patients with RBD are rare and have small sample sizes and heterogeneous populations and methods. 4 Sodium oxybate (SO) has been efficacious in 2 patients with iRBD. 5, 6