Cost Implications of New National Allocation Policy for Deceased Donor Kidneys in the United States. Issue 4 (April 2016)

• Record Type: Journal Article
• Authors: Smith, Jodi M.; Schnitzler, Mark A.; Gustafson, Sally K.; Salkowski, Nicholas J.; Snyder, Jon J.; Kasiske, Bertram L.; Israni, Ajay K.
• Is Part Of: Transplantation. Volume 100:Issue 4(2016)
• Publication Date: 2016-04
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation immunology -- Periodicals; 617.95
• DOI: 10.1097/TP.0000000000001057
• Languages: English
• ISSNs: 0041-1337

Abstract

Abstract : Background: In December 2014, a new national deceased donor kidney allocation policy was implemented, which allocates kidneys in the top 20% of the kidney donor profile index to candidates in the top 20% of expected survival. We examined the cost implications of this policy change. Methods: A Markov model was applied to estimate differences in total lifetime cost of care and quality-adjusted life years (QALY). Results: Under the old allocation policy, average lifetime outcomes per listed patient discounted to 2012 US dollars were US $342 799 and 5.42 QALY, yielding US $63 775 per QALY gained. Under the new policy, average lifetime cost was reduced by US $2090 and lifetime QALYs increased by 0.03. Thus, the new policy improved on the old policy by producing more QALYs at lower cost. The present value of total lifetime cost savings from the policy change is estimated to be US $271 million in the first year and US $55 million in subsequent years. The higher transplant rates and allograft survival expected for candidates in the top 20% of expected survival would decrease costs by reducing time on dialysis. Most cost savings are expected to accrue to Medicare, and most increased access to transplant is expected in private payer populations. Conclusions: The new allocation policy was found to be dominant over the old policy because it increases QALYs at lower cost. Abstract : This pharmacoeconomic analysis using a Markov model with a 20-year time horizon suggests that the new US kidney allocation policy implemented in December 2014 is dominant over the old policy because it is associated with increased quality-adjusted life-years and with lower cost.