Long noncoding RNAs in psychiatric disorders. (June 2016)

• Record Type: Journal Article
• Authors: Zuo, Lingjun; Tan, Yunlong; Wang, Zhiren; Wang, Ke-Sheng; Zhang, Xiangyang; Chen, Xiangning; Li, Chiang-Shan R.; Wang, Tong; Luo, Xingguang
• Is Part Of: Psychiatric genetics. Volume 26:Number 3(2016:Jun.)
• Publication Date: 2016-06
• Subjects: lncRNAs -- psychiatric disorders -- regulation; Mental illness -- Genetic aspects -- Periodicals; Periodicals; 616.89042
• DOI: 10.1097/YPG.0000000000000129
• Languages: English
• ISSNs: 0955-8829

Abstract

Abstract : Long noncoding RNAs (lncRNAs) are nonprotein coding transcripts longer than 200 nucleotides. Many of these lncRNAs have regulatory functions and have recently emerged as major players in governing fundamental biological processes. Here, we review the definition, distribution, identification, databases, analysis, classification, and functions of lncRNAs. We also discuss the potential roles of lncRNAs in the etiological processes of psychiatric disorders and the implications for clinical diagnosis and treatment.