Linchpin dienes: key building-blocks in the synthesis of polyenic frameworks. Issue 14 (11th March 2015)

• Record Type: Journal Article
• Authors: Cornil, J.; Guérinot, A.; Cossy, J.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 14(2015)
• Page Start: 4129
• Page End: 4142
• Publication Date: 2015-03-11
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00154d
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : This review focuses on the preparation of dienic linchpin reagents and on their use in the synthesis of polyenic frameworks. Abstract : A myriad of biologically active products incorporates polyenic frameworks. Among the syntheses developed to access these moieties, metal-catalyzed cross-couplings emerged as reactions of choice especially due to their high stereoselectivity. Particularly, the use of bifunctionalized compounds (linchpin reagents) allows a fast, modular and efficient access to polyenic chains. In this review, we will focus on the preparation of bifunctionalized dienes and on their utilization in the synthesis of polyenes.