Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach. Issue 34 (31st March 2015)
- Record Type:
- Journal Article
- Title:
- Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach. Issue 34 (31st March 2015)
- Main Title:
- Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach
- Authors:
- Zhang, Liyun
Er, Jun Cheng
Li, Xin
Heng, Jun Jie
Samanta, Animesh
Chang, Young-Tae
Lee, Chi-Lik Ken - Abstract:
- Abstract : A novel fluorescent sensor with super selectivity to G-quadruplexes was discovered by the library approach. Abstract : A 241-membered cyanine-based library was constructed by the combinatorial chemistry strategy. Combined with high-throughput screening, we successfully discovered a novel fluorescent probe (CyC-M716) capable of identifying a subset of parallel G-quadruplexes with propeller loops stretching across three tetrad layers with high sensitivity and selectivity.
- Is Part Of:
- Chemical communications. Volume 51:Issue 34(2015)
- Journal:
- Chemical communications
- Issue:
- Volume 51:Issue 34(2015)
- Issue Display:
- Volume 51, Issue 34 (2015)
- Year:
- 2015
- Volume:
- 51
- Issue:
- 34
- Issue Sort Value:
- 2015-0051-0034-0000
- Page Start:
- 7386
- Page End:
- 7389
- Publication Date:
- 2015-03-31
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c5cc01601k ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 4974.xml