Probing extracellular acidity of live cells in real time for cancer detection and monitoring anti-cancer drug activity. Issue 32 (25th March 2015)
- Record Type:
- Journal Article
- Title:
- Probing extracellular acidity of live cells in real time for cancer detection and monitoring anti-cancer drug activity. Issue 32 (25th March 2015)
- Main Title:
- Probing extracellular acidity of live cells in real time for cancer detection and monitoring anti-cancer drug activity
- Authors:
- Thakur, Bhawana
Jayakumar, S.
Sawant, Shilpa N. - Abstract:
- Abstract : A multifunctional platform is presented which (a) allows determination of extracellular pH in real time, (b) detects cancer cells, down to 5 cells, and (c) enables evaluating the efficacy of glycolysis inhibiting drugs. Abstract : We report a novel electrochemical strategy to probe the microenvironment of live cells in real time in terms of its extracellular pH. This approach allowed highly sensitive detection of cancer cells down to five cells. Utility of the sensor for evaluating the efficacy of glycolysis inhibiting anti-cancer drugs is also demonstrated.
- Is Part Of:
- Chemical communications. Volume 51:Issue 32(2015)
- Journal:
- Chemical communications
- Issue:
- Volume 51:Issue 32(2015)
- Issue Display:
- Volume 51, Issue 32 (2015)
- Year:
- 2015
- Volume:
- 51
- Issue:
- 32
- Issue Sort Value:
- 2015-0051-0032-0000
- Page Start:
- 7015
- Page End:
- 7018
- Publication Date:
- 2015-03-25
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c5cc01445j ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 4944.xml