An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine. Issue 30 (16th March 2015)

• Record Type: Journal Article
• Authors: Lee, Dayoung; Kim, Gyoungmi; Yin, Jun; Yoon, Juyoung
• Is Part Of: Chemical communications. Volume 51:Issue 30(2015)
• Page Start: 6518
• Page End: 6520
• Publication Date: 2015-03-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc01071c
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An aryl-thioether substituted nitrobenzothiadiazole probe was synthesized and employed to detect cysteine and homocysteine selectively in living cells. Abstract : An aryl-thioether substituted nitrobenzothiadiazole probe was synthesized and employed to detect cysteine and homocysteine selectively in living cells. Interestingly, both cysteine (Cys) and homocysteine (Hcy) promote an enhancement of the fluorescence intensity of the probe at pH 7.4 while only Cys gives rise to this enhancement under weakly acidic conditions (pH 6.0).