Air pollution and allergic diseases. Issue 6 (December 2015)

• Record Type: Journal Article
• Authors: Brandt, Eric B.; Myers, Jocelyn M. Biagini; Ryan, Patrick H.; Hershey, Gurjit K. Khurana
• Is Part Of: Current opinion in pediatrics. Volume 27:Issue 6(2015:Dec.)
• Publication Date: 2015-12
• Subjects: air pollution -- allergy -- asthma -- traffic pollution; Pediatrics -- Periodicals; Pediatrics -- Periodicals -- Bibliography -- Periodicals; 618.92
• DOI: 10.1097/MOP.0000000000000286
• Languages: English
• ISSNs: 1040-8703

Abstract

Abstract : Purpose of review: Exposure to traffic-related air pollutants (TRAPs) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant because increasingly large segments of the population worldwide reside in zones that have high levels of TRAP, including children, as schools are often located in high traffic pollution exposure areas. Recent findings: Recent findings include epidemiologic and mechanistic studies that shed new light on the impact of traffic pollution on allergic diseases and the biology underlying this impact. In addition, new innovative methods to assess and quantify traffic pollution have been developed to assess exposure and identify vulnerable populations and individuals. Summary: This review will summarize the most recent findings in each of these areas. These findings will have a substantial impact on clinical practice and research by the development of novel methods to quantify exposure and identify at-risk individuals, as well as mechanistic studies that identify new targets for intervention for individuals most adversely affected by TRAP exposure.