A case of cutaneous polyarteritis nodosa with elevated serum interleukin-6 levels complicated by leg arterial stenosis and destructive arthropathy of the left ankle. Issue 1 (January 2014)

• Record Type: Journal Article
• Authors: Horai, Yoshiro; Tokuyama, Ayuko; Sumiyoshi, Remi; Nakashima, Yoshikazu; Suzuki, Takahisa; Okada, Akitomo; Kawashiri, Shin-ya; Ichinose, Kunihiro; Izumi, Yasumori; Miyashita, Taiichiro; Tamai, Mami; Yamasaki, Satoshi; Nakamura, Hideki; Hayashi, Tomayoshi; Origuchi, Tomoki; Kawakami, Atsushi
• Is Part Of: Modern rheumatology. Volume 24:Issue 1(2014)
• Page Start: 206
• Page End: 211
• Publication Date: 2014-01
• Subjects: Arthritis -- Interleukin-6 -- Peripheral artery disease -- Polyarteritis nodosa -- Skin manifestations; Rheumatology -- Periodicals; 616.723005
• DOI: 10.3109/14397595.2013.852840
• Languages: English
• ISSNs: 1439-7595

Abstract

Abstract: We report a case of a 60-year-old female with cutaneous polyarteritis nodosa (CPN) of the left ankle, accompanied by elevated serum interleukin (IL)-6 levels. Computed tomographic angiography revealed severe narrowing of medium-sized arteries in her left leg. Destructive arthropathy in the left ankle was identified by X-ray and magnetic resonance imaging. This is the first Japanese case of severe CPN complicated by destructive arthropathy. Quantification of serum IL-6 might be useful in diagnosis and evaluation of CPN.