Collision cross section measurements for biomolecules within a high-resolution FT-ICR cell: theory. Issue 14 (10th March 2015)

• Record Type: Journal Article
• Authors: Guo, Dan; Xin, Yi; Li, Dayu; Xu, Wei
• Is Part Of: Physical chemistry chemical physics. Volume 17:Issue 14(2015)
• Page Start: 9060
• Page End: 9067
• Publication Date: 2015-03-10
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/c4cp06065b
• Languages: English
• ISSNs: 1463-9076

Abstract

Abstract : An energetic hard-sphere collision model for modern high-resolution FT-ICR. Abstract : In this study, an energetic hard-sphere ion–neutral collision model was proposed to bridge-link ion collision cross section (CCS) with the image current collected from a high-resolution Fourier transform ion cyclotron resonance (FT-ICR) cell. By investigating the nonlinear effects induced by high-order electric fields and image charge forces, the energetic hard-sphere collision model was validated through experiments. Suitable application regions for the energetic hard-sphere collision model, as well as for the conventional Langevin and hard-sphere collision models, were also discussed. The energetic hard-sphere collision model was applied in the extraction of ion CCSs from high-resolution FT-ICR mass spectra. Discussions in the present study also apply to FT-Orbitraps and FT-quadrupole ion traps.