Comparison of toxicity after IMRT and 3D-conformal radiotherapy for patients with pancreatic cancer – A systematic review. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Bittner, Martin-Immanuel; Grosu, Anca-Ligia; Brunner, Thomas B.
• Is Part Of: Radiotherapy and oncology. Volume 114:Issue 1(2015:Jan.)
• Page Start: 117
• Page End: 121
• Publication Date: 2015-01
• Subjects: IMRT -- Pancreatic cancer -- Radiotherapy planning -- Toxicity; Oncology -- Periodicals; Radiotherapy -- Periodicals; Tumors -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiothérapie -- Périodiques; Cancérologie -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9940642
• DOI: 10.1016/j.radonc.2014.11.043
• Languages: English
• ISSNs: 0167-8140

Abstract

Summary: IMRT has been suggested to reduce treatment-related toxicity in pancreatic cancer. We attempted to identify all IMRT-studies indexed in PubMed/Medline, comparing them with recent 3D-CRT trials. The predominant treatment-related toxicities, namely nausea/vomiting, diarrhoea and late GI toxicity, are significantly reduced with IMRT while there was no apparent difference for outcome measures.