Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays. Issue 11 (November 2017)

• Record Type: Journal Article
• Authors: Mattiasson, B.; Teeparuksapun, K.; Lebogang, L.; Hedström, M.
• Is Part Of: Trends in biotechnology. Volume 35:Issue 11(2017)
• Page Start: 1021
• Page End: 1024
• Publication Date: 2017-11
• Subjects: nanoenvironment -- capacitive biosensor -- immunoassay -- ultrasensitive; Biotechnology -- Periodicals; Biochemical engineering -- Periodicals; Genetic engineering -- Periodicals; Industrial microbiology -- Periodicals; 660.605
• DOI: 10.1016/j.tibtech.2017.06.001
• Languages: English
• ISSNs: 0167-7799

Abstract

Abstract : It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using 'normal' antibodies (Abs).