A method for the comparison of multi-platform spectral histopathology (SHP) data sets. Issue 7 (9th February 2015)

• Record Type: Journal Article
• Authors: Ergin, Ayşegül; Großerüschkamp, Frederik; Theisen, Oliver; Gerwert, Klaus; Remiszewski, Stan; Thompson, Clay M.; Diem, Max
• Is Part Of: Analyst. Volume 140:Issue 7(2015)
• Page Start: 2465
• Page End: 2472
• Publication Date: 2015-02-09
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c4an01879f
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : Results of a study comparing infrared imaging data sets collected on different instruments or instrument platforms are reported, along with detailed methods developed to permit such comparisons. Abstract : Results of a study comparing infrared imaging data sets collected on different instruments or instrument platforms are reported, along with detailed methods developed to permit such comparisons. It was found that different instrument platforms, although employing different detector technologies and pixel sizes, produce highly similar and reproducible spectral results. However, differences in the absolute intensity values of the reflectance data sets were observed that were caused by heterogeneity of the sample substrate in terms of reflectivity and planarity.