Abstract : Through Ru(ii )-catalyzed C–H activation, a methodology for the synthesis of 2- or 2, 7-functionalized pyrene derivatives has been developed. Abstract : Through Ru(ii )-catalyzed C–H bond activation, a methodology for the synthesis of 2- or 2, 7-functionalized pyrene derivatives has been developed using the substrate 1-(pyrid-2-yl)pyrene or 1, 6-di(pyrid-2-yl)pyrene.