Increased expression of vascular endothelial growth factor and its receptor in enlarging brain arteriovenous malformations – a case report. (February 2014)

• Record Type: Journal Article
• Authors: Kashiwazaki, Daina; Kobayashi, Rina; Houkin, Kiyohiro; Kuroda, Satoshi
• Is Part Of: British journal of neurosurgery. Volume 28:Number 1(2014:Feb.)
• Page Start: 119
• Page End: 121
• Publication Date: 2014-02
• Subjects: angiogenesis -- BAVMs -- enlarging -- VEGF -- VEGF-R; Nervous system -- Surgery -- Periodicals; 617.48
• DOI: 10.3109/02688697.2013.815325
• Languages: English
• ISSNs: 0268-8697

Abstract

Abstract: Case . A 24-year-old man with Spetzler–Martin (S–M) Grade III arteriovenous malformation (AVM). He was conservatively treated, but AVM significantly increased in size over 5 years, judged as Grade IV. Subsequently, he developed intracerebral hemorrhage. AVM was totally removed. Immunohistochemistry showed that the endothelial cells in the dura and nidus were positive for VEGF and VEGF-R.