Prognostic value of copeptin in patients with acute stroke. (May 2015)

• Record Type: Journal Article
• Authors: Jiao, Lidong; Chu, Changbiao; Zhou, Shijie
• Is Part Of: Expert review of neurotherapeutics. Volume 15:Number 5(2015)
• Page Start: 563
• Page End: 570
• Publication Date: 2015-05
• Subjects: acute stroke -- copeptin -- prognosis -- systematic review; Neuropharmacology -- Periodicals; 615.7805
• DOI: 10.1586/14737175.2015.1030734
• Languages: English
• ISSNs: 1473-7175

Abstract

Abstract : Context: There is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome. Objective: To evaluate the prognostic value of copeptin in patients with stroke. Methods: We systematically searched PubMed and Embase for relevant studies. Poor outcome and mortality were analyzed. Results: Twelve studies, containing 2682 patients, were included. Pooled analysis showed that copeptin is an independent prognostic marker of poor outcome after acute stroke and there is a borderline effect of copeptin in predicting mortality after acute stroke. Conclusions: Copeptin is an independent predictor of poor outcome and mortality for patients with acute stroke.