Colorimetric and fluorescent probe for real-time detection of palladium (II) ion in aqueous medium and live cell imaging. (January 2018)

• Record Type: Journal Article
• Authors: Chen, Xiangzhu; Wang, Hongmei; Ma, Xiaodong; Wang, Mian; Zhang, Yuanyuan; Gao, Gui; Liu, Jingjing; Hou, Shicong
• Is Part Of: Dyes and pigments. Volume 148(2018)
• Page Start: 286
• Page End: 291
• Publication Date: 2018-01
• Subjects: Coumarin oxime -- Sulfur atom -- Palladium (II) ion -- Aqueous solution -- Fluorescence imaging; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2017.08.063
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: A novel fluorescent and colorimetric sensor (WM-S ) was synthesized from coumarin oxime and 2-chloroethyl methyl sulfide in a straightforward manner. The sensor displayed high selectivity for detection of Pd 2+ over other metal ions (Cu 2+ and Hg 2+ in particular). The probe also exhibited high sensitivity for recognition of Pd 2+ in aqueous media and can detect trace amounts of Pd 2+ in real time, with a detection limit as low as 41.5 nM. Fluorescence imaging experiments of Pd 2+ in HeLa cells indicated that the sensor can penetrate cell membranes and effectively detect intracellular Pd 2+ . Graphical abstract: Highlights: A new fluorescent probe that can detect trace amounts of Pd(II) ions in real time in aqueous media was synthesized. The probe displayed the high selectivity towards Pd 2+ over other metal ions (Cu 2+ and Hg 2+ in particular). The probe showed good cell permeability and Pd 2+ could be detected within the cells.