Accuracy of administrative claims data to identify dose specific rotavirus vaccination information: Implications for studies of vaccine safety. Issue 22 (21st May 2015)

• Record Type: Journal Article
• Authors: Quinlan, Scott C.; Lanes, Stephan; Holick, Crystal N.; Mast, T. Christopher
• Is Part Of: Vaccine. Volume 33:Issue 22(2015)
• Page Start: 2517
• Page End: 2520
• Publication Date: 2015-05-21
• Subjects: Rotavirus vaccination -- Administrative claims -- Validation -- Positive predictive value -- Safety; CI confidence interval -- CPT Current Procedural Terminology -- HIRD HealthCore Integrated Research DatabaseSM -- PPV positive predictive value -- RV1 Rotarix® -- RV5 RotaTeq®; Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.04.009
• Languages: English
• ISSNs: 0264-410X

Abstract

Abstract: Background: The accuracy of vaccine administration information recorded in administrative claims databases is uncertain. Methods: We conducted a retrospective cohort study using the HealthCore Integrated Research Database SM among infants who received at least 1 RotaTeq ® (RV5) dose during the first year of life between February 1, 2006 and November 30, 2012 and were enrolled in the health plan at birth. We reviewed medical records for a sample of infants to validate vaccine administration information. Results: We identified 169, 560 infants who received at least 1 RV5 dose. Medical records were obtained for 85 infants, of which 74 (PPV1 87.1%; 95% CI 78.0–93.4%) had a corresponding first RV5 vaccination in the medical record with the same or similar administration date. Conclusions: Administrative claims contained inaccuracies in dose number or administration date for 13% of RV5 first doses identified.