Emergence and Distribution of Foot‐and‐Mouth Disease Virus Serotype A and O in Bangladesh. Issue 3 (4th June 2013)

• Record Type: Journal Article
• Authors: Nandi, S. P.; Rahman, M. Z.; Momtaz, S.; Sultana, M.; Hossain, M. A.
• Is Part Of: Transboundary and emerging diseases. Volume 62:Issue 3(2015)
• Page Start: 328
• Page End: 331
• Publication Date: 2013-06-04
• Subjects: foot‐and‐mouth disease virus -- distribution -- serotype -- Bangladesh; Veterinary medicine -- Periodicals; 636.089
• DOI: 10.1111/tbed.12113
• Languages: English
• ISSNs: 1865-1674

Abstract

Summary: Foot‐and‐mouth disease (FMD) is endemic in Bangladesh and is predominantly due to FMDV serotype O. In 2012, FMD outbreaks were identified in five different districts of Bangladesh. Of 56 symptomatic cattle epithelial tissue samples, diagnostic PCR assay based on 5′‐URT detected 38 FMDV infections. Viral genotyping targeting VP1‐encoding region confirmed emergence of two distinct serotypes, A and O with an abundance of serotype A in Chittagong and Gazipur districts and serotype O in Pabna and Faridpur. Only single lineage of both A and O was retrieved from samples of five different regions. Sequencing and phylogenetic analysis of VP1 sequences revealed that serotype O sequences were closely related to the Ind 2001 sublineage of Middle East–South Asia (ME‐SA) topotype that was previously circulating in Bangladesh, and serotype A sequences belonging to the genotype VII that was dominant in India during the last decade. The results suggest that extensive cross‐border animal movement from neighbouring countries is the most likely source of FMDV serotypes in Bangladesh.