Airway plaque presenting after alteration of immunosuppression in a pediatric patient remote from heart transplantation. (24th August 2017)

• Record Type: Journal Article
• Authors: Ryan, Thomas D.; Absalon, Michael J.; de Alarcon, Alessandro; Gupta, Anita; Peters, Anna L.; Lorts, Angela; Danziger‐Isakov, Lara A.; Chin, Clifford
• Is Part Of: Pediatric transplantation. Volume 21:Number 7(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-08-24
• Subjects: airway -- EBV -- heart transplant -- immunosuppression -- mTOR inhibitor -- post‐transplant lymphoproliferative disorder; Transplantation of organs, tissues, etc. in children -- Periodicals; 617.95408305
• DOI: 10.1111/petr.13046
• Languages: English
• ISSNs: 1397-3142

Abstract

Abstract: Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9‐year‐old girl, remote from transplant, who presented with airway plaque after a change in immunosuppression to include the mTOR inhibitor sirolimus. Differential diagnosis included direct medication side effect, infection, and neoplasia.