Radiotherapy with soft X‐rays in Dupuytren's disease – successful, well‐tolerated and satisfying. (8th September 2014)

• Record Type: Journal Article
• Authors: Zirbs, M.; Anzeneder, T.; Bruckbauer, H.; Hofmann, H.; Brockow, K.; Ring, J.; Eberlein, B.
• Is Part Of: Journal of the European Academy of Dermatology and Venereology. Volume 29:Number 5(2015:May)
• Page Start: 904
• Page End: 911
• Publication Date: 2014-09-08
• Subjects: Dermatology -- Periodicals; Sexually transmitted diseases -- Periodicals; 616.5
• DOI: 10.1111/jdv.12711
• Languages: English
• ISSNs: 0926-9959

Abstract

Abstract: Background: Up to present no curative treatment is known for Dupuytren's disease (DD). Surgery remains the most common treatment but lack of long‐term efficacy and complications limit this therapeutic option. Objective: In a retrospective analysis, the results of radiotherapy with soft X‐rays in the treatment of DD were evaluated. Methods: A total of 206 patients (297 affected hands) with DD were included. Radiation therapy was carried out with soft X‐rays. A structured questionnaire considering patient and disease characteristics and effects of radiotherapy was evaluated after a median follow‐up time of 40 months. Results: Ninety‐three (45%) of the 206 treated patients were reported on a regression of symptoms after radiation. No further disease progression (including patients with regression) was present in 165 patients (80%). Satisfaction with the therapy was expressed with an average score of 7.9 points (visual analogue scale, 0 = not satisfied, 10 = extremely satisfied). Subjective therapeutic effects for 426 nodules and/or cords showed a reduction of 92 nodules and/or cords. Conclusion: In 206 DD patients further disease progression was stopped in most patients. Radiotherapy proved to be well‐tolerated, successful and satisfying for the patients.