Carbothioamide as Highly Efficient Ligand for Copper‐catalyzed Room Temperature Chan–Lam Cross‐Coupling Reaction. (26th September 2017)

• Record Type: Journal Article
• Authors: Baruah, Jayantajit; Gogoi, Kongkona; Dewan, Anindita; Borah, Geetika; Bora, Utpal
• Is Part Of: Bulletin of the Korean Chemical Society. Volume 38:Number 10(2017)
• Page Start: 1203
• Page End: 1208
• Publication Date: 2017-09-26
• Subjects: Imidazole -- Arylboronic acid -- 2‐(4‐methoxybenzylidene)‐N‐phenylhydrazinecarbothioamide -- 2, 2′‐(1, 2‐diphenylethane‐1, 2‐diylidene)bis(hydrazinecarbothioamide) -- 2‐(4‐methoxybenzylidene)hydrazinecarbothioamide -- N‐arylation; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/bkcs.11248
• Languages: English
• ISSNs: 0253-2964

Abstract

Abstract : The catalytic activity of three N, S‐donor ligands, viz L1 [2‐(4‐methoxybenzylidene)‐ N ‐phenylhydrazinecarbothioamide], L2 [2, 2′‐(1, 2‐diphenylethane‐1, 2‐diylidene)bis(hydrazinecarbothioamide)] and L3 [2‐(4‐methoxybenzylidene)hydrazinecarbothioamide] has been reported for N‐arylation of imidazoles with arylboronic acids in ethanol at room temperature. The method was found to be applicable in N‐arylation for a wide range of electronically diverse arylboronic acids with imidazoles having modest to excellent isolated yields. The in situ generated copper(II) complex of the ligand namely, 2‐(4‐methoxybenzylidene)‐ N ‐phenylhydrazinecarbothioamide (L1) was found to be highly efficient homogeneous catalyst for N‐arylation reaction. Abstract :