Phosphorylation is required for the pathogen defense function of the Arabidopsis PEN3 ABC transporter. (3rd October 2017)

• Record Type: Journal Article
• Authors: Underwood, William; Somerville, Shauna C.
• Is Part Of: Plant signaling & behavior. Volume 12:Number 10(2017)
• Publication Date: 2017-10-03
• Subjects: Defense response -- powdery mildew -- pattern-triggered immunity -- pattern-recognition receptor -- papilla -- signal transduction; Plant ecophysiology -- Periodicals; Plant cellular signal transduction -- Periodicals; Plant cellular signal transduction; Plant ecophysiology; Periodicals; Electronic journals; 581
• DOI: 10.1080/15592324.2017.1379644
• Languages: English
• ISSNs: 1559-2316

Abstract

ABSTRACT: The Arabidopsis PEN3 ABC transporter accumulates at sites of pathogen detection, where it is involved in defense against a number of pathogens. Perception of PAMPs by pattern recognition receptors initiates recruitment of PEN3 and also leads to PEN3 phosphorylation at multiple amino acid residues. Whether PAMP-induced phosphorylation of PEN3 is important for its defense function or focal recruitment has not been addressed. In this study, we evaluated the role of PEN3 phosphorylation in modulating the localization and defense function of the transporter. We report that PEN3 phosphorylation is critical for its function in defense, but dispensable for recruitment to powdery mildew penetration sites. These results indicate that PAMP-induced phosphorylation is likely to regulate the transport activity of PEN3.