Influence of crystallite size on the magnetic and heat generation properties of La0.77Sr0.23MnO3 nanoparticles for hyperthermia applications. (January 2018)

• Record Type: Journal Article
• Authors: Das, Harinarayan; Inukai, Akihiro; Debnath, Nipa; Kawaguchi, Takahiko; Sakamoto, Naonori; Hoque, Sheikh Manjura; Aono, Hiromichi; Shinozaki, Kazuo; Suzuki, Hisao; Wakiya, Naoki
• Is Part Of: Journal of physics and chemistry of solids. Volume 112(2018)
• Page Start: 179
• Page End: 184
• Publication Date: 2018-01
• Subjects: LSMO -- Magnetic hyperthermia -- Heat generation ability -- Relaxation loss; Solids -- Periodicals; Solides -- Périodiques; Solids; Periodicals; 530.41
• DOI: 10.1016/j.jpcs.2017.09.030
• Languages: English
• ISSNs: 0022-3697

Abstract

Abstract: In this paper, we report a detailed study of magnetic properties and AC magnetic heat generation characteristics of La0.77 Sr0.23 MnO3 (LSMO) nanoparticles to investigate appropriate crystallite size with a view to the proper application of self-controlled magnetic hyperthermia treatments of cancer. A series of nanocrystalline LSMO manganite was synthesized through the chemical route called as "polymerized complex method" and then subsequently annealed at the different temperature from 600 to 1400 °C to obtain various crystallite size. Phase formation and crystal structure of the prepared powder were determined by the powder X-ray diffraction (XRD) using Rietveld analysis. The XRD patterns reveal that all powder samples are a single phase rhombohedral perovskite-like structure with R 3 ¯ c space group. The mean crystallite size of prepared particles varied from 19 to 243.8 nm with the increase of the annealing temperature starting from 600 to 1400 °C. The field emission scanning electron microscopy (FE-SEM) analysis shows the surface morphology with a strong agglomeration of fine nanoparticles. The Magnetic study reveals that these nanoparticles exhibit ferromagnetic nature with different value of magnetization, coercivity, Curie temperature which is strongly dependent on their crystallite size. The maximum saturation temperature ( T S = 66 °C) under AC magnetic field ( H = 1.77 kA/m, f = 370 kHz) was found for the crystallite size of 39.5 nm due to its pure single domain phase. Such LSMO nanoparticles, having the higher heating rate, can be used in magnetically induced hyperthermia cancer treatment. Graphical abstract: Highlights: La0.77 Sr0.23 MnO3 nanoparticles were synthesized by polymerized complex method. Distinguish the single and multi-domain size of synthesized nanocrystallites. Optimal crystallite size of LSMO nanoparticles for higher heat generation rate was clarified.