Synthetic profile of thiadiazoloquinazolines. (2nd November 2017)

• Record Type: Journal Article
• Authors: Abdel-Wahab, Bakr F.; Farahat, Abdelbasset A.; Bekheit, Mohamed S.
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 192:Number 11(2017)
• Page Start: 1165
• Page End: 1170
• Publication Date: 2017-11-02
• Subjects: Thiadiazole -- quinazoline -- thiadiazolo[3, 2-a]quinazoline -- thiadiazolo[3, 2-b]quinazolin -- thiadiazolo[3, 2-c]quinazoline; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2017.1354213
• Languages: English
• ISSNs: 1042-6507

Abstract

GRAPHICAL ABSTRACT: ABSTRACT: According to the biological screening reports, a thiadiazoloquinazoline scaffold constitutes a promising source of inspiration for the synthesis of novel bioactive molecules. The current review article summarizes the most recent synthetic routes toward thiadiazoloquinazoline derivatives. According to the position of fusion between the thiadiazole and quinazoline rings, thiadiazoloquinazoline derivatives are classified into three major types, thiadiazolo[2, 3- b ]quinazolines, thiadiazolo[3, 2- a ]quinazolines and thiadiazolo[3, 2- c ]quinazolines.