CAN-catalyzed microwave promoted reaction of indole with Betti bases under solvent-free condition and evaluation of antibacterial activity of the products. Issue 21 (2nd November 2017)

• Record Type: Journal Article
• Authors: Pegu, Choitanya Dev; Nasrin, Sheikh Benazir; Deb, Mohit L.; Das, Deep Jyoti; Saikia, Kandarpa K.; Baruah, Pranjal K.
• Is Part Of: Synthetic communications. Volume 47:Issue 21(2017)
• Page Start: 2007
• Page End: 2014
• Publication Date: 2017-11-02
• Subjects: Betti base -- CAN-catalyzed -- 3-(α, α-diarylmethyl)indoles -- microwave -- solvent-free; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2017.1360912
• Languages: English
• ISSNs: 0039-7911

Abstract

ABSTRACT: CAN-catalyzed reaction of Betti bases with indoles under microwave irradiation gives 3-( α, α -diarylmethyl)indoles. Better yield of the products, especially when one of the aryl ring is phenol were achieved. The reaction is performed in solvent-free condition. The antibacterial studies of the synthesized compounds were performed and some of the compounds showed good activity against Methicillin-resistant Staphylococcus aureus bacteria. GRAPHICAL ABSTRACT: