[PP.28.23] RELATIONSHIP BETWEEN HYPERTENSION AND GENDER IN PATIENTS WITH DIABETES MELLITUS. (September 2017)

• Record Type: Journal Article
• Authors: Avramescu, C.; Iancu, M.A.; Dediu, G.N.; Diaconu, C.C.; Matei, D.
• Is Part Of: Journal of hypertension. Volume 35(2017)Supplement 2
• Publication Date: 2017-09
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000523952.21773.b7
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: Most patients with tip II diabetes melittus develop hypertension during their life. Arterial hypertension has a high impact on the incidence and prevalence of complications in patients with diabetes mellitus. The aim of this study was to assess the impact of gender differences on the complications in the diabetes mellitus patients, depending on the presence of hypertension. Design and method: In this observational study conducted during January to December 2016, we included 129 patients with diabetes mellitus (87 men and 42 women), included in the records of a family medicine office. From these patients, 105 had hypertension (group 1) and 24 had normal blood pressure (group 2). The following characteristics of the two groups of patients were comparatively analyzed: fasting plasma glucose, the positive family history of hypertension, premature cardiovascular disease and diabetes, and frequency of diabetes' complications. Results: Men were younger than women (mean age 57.75 ± 11.4 years versus 66 ± 11.7 years). The prevalence of hypertension in men was 86.20%, higher than in women (71.42%). The comparative distribution of diabetic complications in women and men was: diabetic retinopathy (14.28% vs 6.89%), diabetic nephropathy (7.14% vs 13.79%) and diabetic neuropathy (21.42% vs 27.58%). The prevalence of diabetic nephropathy was significantly higher in patients with diabetes mellitus and hypertension (p = 0.001). Not a single case of diabetic retinopathy or diabetic neuropathy was encountered in the group of patients with diabetes and normal blood pressure (group 2). Patients from group 1 (with diabetes mellitus and hypertension) had a family history of premature cardiovascular disease (p = 0.012) and diabetes (p = 0.006) statistically significantly higher than patients from group 2. Conclusions: Both fastum glucose level and blood pressure control are important in preventing diabetes' complications. The presence of hypertension is a risk factor for diabetic nephropathy, especially in men. The frequency of diabetic retinopathy was higher in women, in our study. The family history of premature cardiovascular disease and diabetes is a risk factor for further development of hypertension in diabetic patients.