[PP.27.21] HYPERTENSION AND PRIMARY ALDOSTERONISM. (September 2017)

• Record Type: Journal Article
• Authors: Dammak, N.; Guesmi, R.; Chaabouni, Y.; Mahfoudh, H.; Yaich, S.; M. B.Hmida, ; Kharrat, M.; Jarraya, F.; Kammoun, K.; Hachicha, J.
• Is Part Of: Journal of hypertension. Volume 35(2017)Supplement 2
• Publication Date: 2017-09
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000523934.66622.eb
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: At the age of 45 years, more than 50% of the population suffers from hypertension. It is in most cases essential. However, in some situations, a secondary origin must be sought. Primary hyperaldosteronism is the most frequent cause after nephropathy. Design and method: Our study is retrospective on a year (March 2015-March 2016), including hypertensive patients who received a renal aldosterone (R/A) assay in the presence of secondary hypertension after eliminating unilateral or bilateral parenchymal nephropathy. Results: We collected sixteen patients with an average age 46 years. The average seniority of the high blood pressure was 3 years. primary hyper aldosternism was suspected face to a hypertension associated wih hypokalaemia in 10 cases, in front of a resistant hypertension in 4 cases and before the fortuitous discovery of an adrenal nodule in 2 patients. The results of the assays were in favor of a primary hyper aldosternism on average in 8 patients A/R ratio up to 28 according to the usual values of the laboratory). An adrenal nodule was found in 6 of these patients. Therapeutic management was adrenalectomy in 2 of these patients, and spironolacton treatment for the others. Conclusions: Primary hyperaldosteronism is probably under-diagnosed and affects about 10% of hypertensive patients. The earlier diagnosis, the more likely avoiding cardiovascular and renal complications.