[PP.15.11] EVALUATION OF AFFECTIVE TEMPERAMENTS, DEPRESSION AND ANXIETY IN WHITE-COAT, WELL-TREATED AND RESISTANT HYPERTENSION AND IN HEALTHY CONTROLS. (September 2017)

• Record Type: Journal Article
• Authors: Nemcsik, J.; Korosi, B.; Batta, D.; Laszlo, A.; Tabak, A.; Eorsi, D.; Torzsa, P.; Cseprekal, O.; Tisler, A.; Nemcsik-Bencze, Z.S.; Gonda, X.; Rihmer, Z.
• Is Part Of: Journal of hypertension. Volume 35(2017)Supplement 2
• Publication Date: 2017-09
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000523591.86465.03
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: Hypertension and mood disorders both increase the frequency of cardiovascular events. Affective temperaments are related to mood disorders, however, less data are available about the relationship between affective temperaments and cardiovascular diseases. The aim of this study was to evaluate affective temperament scores, depression, anxiety, hemodynamic and arterial stiffness parameters in healthy subjects (Cont), as well as in chronic, well-treated (Chr), chronic, resistant (Res) and white-coat (Wh) hypertensive patient populations. Design and method: In our study, 261 patients were included: 148 Chr, 29 Res, 17 Wh and 67 Cont subjects. The patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A), the Beck Depression Inventory (BDI) and the Hamilton Anxiety Scale (HAMA). Blood pressure was measured with a validated oscillometric device (Omron M3) and arterial stiffness was examined with tonometry (PulsePen). Results: Significant differences were found between the Cont, Chr, Res and Wh in brachial systolic blood pressure (121.44 ± 11.1, 131.66 ± 12.16, 151.1 ± 27.92, 136.31 ± 12.31 mmHg, respectively) and in pulse wave velocity (7.78 ± 1.39, 9.24 ± 2.19, 10.49 ± 2.76, 8.06 ± 1.61 m/s, resp.). In cyclothymic affective temperament scores we found significant differences between the Cont, Chr and Res groups (2(0–4), 3(1–5), 4(3–8), resp.) with the highest score in Res. In BDI scores also significant differences were found between Cont, Chr and Res (3(0–5), 5(2–9), 7(4–12.5), resp.), while in HAMA scores differences between Cont, Chr, Res and Wh (3(1–6), 5(2–9), 12 (6–19.5), 8(5–10.5), resp.) groups were found. Res group showed the worst BDI and HAMA profiles as well. Conclusions: Evaluation of affective temperaments might be helpful in identification of high-risk subgroups of hypertensive patients. However, prospective studies are required to confirm these observations.